Sym-021
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Sym-021 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. Sym-021 blocks the binding of PD-L1 and PD-L2 ligands, inducing the secretion of interferon IFN-γ and IL-2 and the proliferation of T cells. Sym-021 has anti-tumor activity in PDX mouse models[1].
12352203
PD-1/PD-L1
Immunology/Inflammation
Cancer-programmed cell death
Cancer
[Sym-021]
[1]Gjetting T, et al. Sym021, a promising anti-PD1 clinical candidate antibody derived from a new chicken antibody discovery platform. MAbs. 2019 May/Jun;11 (4) :666-680.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991353/
Inhibitory Antibodies
No Development Reported
Beschrijving
Sym-021 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. Sym-021 blocks the binding of PD-L1 and PD-L2 ligands, inducing the secretion of interf
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