SYMPK Antilichaam - middengebied: Biotine (ARP42901 P050-Biotine)

Symplekin

SPK, SYM

8189

Q92797

NP_004810

Human, Rat, Pig

The immunogen is a synthetic peptide directed towards the middle region of human SYMPK

SYMPK is a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

KAT6A; VCP; KMT2A; UBC; WWOX; RPA3; RPA2; RPA1; SSU72; CPSF2; CPSF3; TOP1; SUMO1; SIRT7; SUMO2; SMARCAD1; CSTF2; HTT; HSF1

Biotin

Polyclonal Antibody

WB

Affinity Purified

SYMPK is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Human: 100%; Pig: 79%; Rat: 82%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

141kDa

Cao, Y., (2007) Histopathology 51 (4), 528-538

Wet Ice

1274

SYMPK

SYMPK

Rabbit

Symplekin

NM_004819

GPLPKETAAGGLTLKEERSPQTLAPVGEDAMKTPSPAAEDAREPEAKGNS