Synaptotagmin (fosfo Thr202) Antilichaam

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.

6857

P21579

NP_001129277.1

Human, Mouse, Rat

Synaptotagmin (phospho Thr202) antibody was raised against a peptide sequence around phosphorylation site of threonine 202 (R-K-T (p) -L-N) derived from Human Synaptotagmin.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

60 kDa

IgG

The antibody detects endogenous levels of Synaptotagmin only when phosphorylated at threonine 202.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

SYT1

Synaptotagmin I

Homo sapiens

E Carafoli, Crit. Rev. Biochem. Mol. Biol., Apr 2001; 36: 107.

Gry Houeland, J Neurophysiol, Jan 2007; 97: 134 - 143.

Christelle Carteron, J. Cell Sci., Mar 2006; 119: 898 - 909.

Vladimir I. Slepnev, Science, Aug 1998; 281: 821.

LAG, LAP18, STN1, Prosolin, stathmin

WB, IHC

5032139

Liquid