Syndecaan 1 (SDC1) Mouse Monoklonale Antilichaam [Kloon ID: LBI1B6]

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008].

Carrier-free (BSA/glycerol-free) SDC1 mouse monoclonal antibody, clone LBI1B6

CD138; SDC; SYND1; syndecan

Homo sapiens syndecan 1 (SDC1), transcript variant 1, mRNA.

6382

P18827

Unconjugated

Cell adhesion molecules (CAMs), ECM-receptor interaction

Cell adhesion molecules (CAMs), ECM-receptor interaction

WB 1:500-1000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

SDC1

https://www.ncbi.nlm.nih.gov/gene/?term=6382

https://www.uniprot.org/uniprot/P18827