SYNPO2L Antilichaam

SYNPO2L Antibody: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.

79933

Q9H987

BAD37139

Human, Mouse

Unconjugated

Primary Antibodies

Signal Transduction

SYNPO2L Antibody is affinity chromatography purified via peptide column.

Cat. No. 1314 - Human Thymus Tissue Lysate

1 mg/mL

SYNPO2L Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SYNPO2L antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

SYNPO2L

Synaptopodin 2-like

Homo sapiens

Beqqali A, Kloots J, Ward-van Oostward D, et al. Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes. Stem Cells2006; 24:1956-67.

Beqqali A, Manshouwer-Kloots J, Moneiro R, et al. CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function. J. Cell Sci.2010; 123:1141-50.

SYNPO2L Antibody: Synaptopodin 2-like protein

ELISA, WB, IF

51534920

Liquid