Syntaxine 1a (STX1A) Mouse Monoclonal Antibody [Kloon ID: LBI7E2]

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Carrier-free (BSA/glycerol-free) STX1A mouse monoclonal antibody, clone LBI7E2

HPC-1; P35-1; STX1; SYN1A

Homo sapiens syntaxin 1A (STX1A), transcript variant 1, mRNA.

6804

Q16623

Unconjugated

SNARE interactions in vesicular transport

SNARE interactions in vesicular transport

WB 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Secreted Protein, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

STX1A

https://www.ncbi.nlm.nih.gov/gene/?term=6804

https://www.uniprot.org/uniprot/Q16623