SYVN1 Antilichaam - C-terminaal gebied: Biotine (ARP43361 P050-Biotine)

Synovial apoptosis inhibitor 1, synoviolin

DER3, HRD1

84447

Q86TM6

NP_115807

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the C terminal region of human SYVN1

SYVN1 is a protein involved in endoplasmic reticulum (ER) -associated degradation. The protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.This gene encodes a protein involved in endoplasmic reticulum (ER) -associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.

Rer1; OS9; SEL1L; STXBP5L; UBC; SYVN1; DERL2; HEY2; HEY1; USP19; Ube2g2; MARCH6; VCP; YOD1; ATXN3; DERL1; HERPUD1; TP53; BSG; ASGR1; GPR37; UBE2D3; UBE2D2; USP7; ATN1; APOB; ERLEC1; UBXN8; SHH; ERN1; ASGR2; SARAF; FAM8A1; TYR; AUP1; ERLIN2; SGK1; ATP6AP1

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 85%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

67kDa

Cattaneo, M., (2008) J. Cell. Physiol. 215 (3), 794-802

Wet Ice

616

SYVN1

SYVN1

Rabbit

E3 ubiquitin-protein ligase synoviolin

NM_032431

ARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVV