T-Boc-N-amido-PEG4-Val-Cit
Gecertificeerd

T-Boc-N-amido-PEG4-Val-Cit

Catalog #: TYD-01998-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

CAS Number

2231240-82-5

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

T-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker, featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit dipeptide is susceptible to cleavage by cellular proteases and contains a free carboxylic acid that can couple with amines to form amides. The Boc group can be removed under acidic conditions to reveal a free primary amine, which is useful for various reactions, such as conjugation or reductive amination.

Smiles

[C@H](C(N[C@@H](CCCNC(N)=O)C(O)=O)=O)(NC(CCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O)[C@@H](C)C

Molecular Formula

C27H51N5O11

Molecular Weight

621.721

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

T-Boc-N-amido-PEG4-Val-Cit Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamT-Boc-N-amido-PEG4-Val-Cit
Categorie
Beschikbare grootte10 mg
CatalogusnummerTYD-01998-01