T-Boc-N-amido-PEG4-Val-Cit
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
T-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit dipeptide is cleavable by cell proteases and features a carboxylic acid which is free for coupling reactions with amines to form amides. The Boc can be removed under acidic conditions to reveal a free primary amine, which may be used in a variety of reactions such as coupling or reductive amination.
2231240-82-5
12352203
H302-H315-H319-H335
ADC Linker
Antibody-drug Conjugate/ADC Related
Cancer
NC(NCCC[C@@H](C(O)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O)=O)=O
C27H51N5O11
621.72
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W800837/
ADC Related
No Development Reported
Beschrijving
T-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit di
Specificaties
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