TAB2-eiwit, humaan, recombinant (zijn & Myc)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF) . Acts as an adapter linking MAP3K7/TAK1 and TRAF6 to 'Lys-63'-linked polyubiquitin chains. The RanBP2-type zinc finger (NZF) specifically recognizes Lys-63'-linked polyubiquitin chains unanchored or anchored to the substrate proteins such as RIPK1/RIP1: this acts as a scaffold to organize a large signaling complex to promote autophosphorylation of MAP3K7/TAK1, and subsequent activation of I-kappa-B-kinase (IKK) core complex by MAP3K7/TAK1. Regulates the IL1-mediated translocation of NCOR1 out of the nucleus. Involved in heart development.
Ice Packs
-20°C
Beschrijving
TAB2-eiwit, humaan, recombinant (zijn & Myc) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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