TADA2L Antilichaam - middengebied: Biotine (ARP38045_P050-Biotin)

Transcriptional adaptor 2A

ADA2, ADA2A, KL04P, hADA2, TADA2L

6871

O75478

NP_001479

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human TADA2L

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene.

MFAP1; MAGOH; KPNA2; FBF1; PRPF31; PPP1R16B; ZFYVE26; SF3A3; FARS2; MTX2; EIF4E2; FAM127C; KLHL38; TTC9C; ZNF564; TEKT4; LOC149950; KLC4; TTC23; GPSM3; CDCA7L; C1orf109; CCHCR1; PRKAB2; ARNT2; USP22; TADA3; HNF4A; LYN; HSP90AA1; KAT2B; MCPH1; PAXIP1; SUPT

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

51kDa

Yang, M., (2008) Cancer Biol. Ther. 7 (1), 120-128

Wet Ice

443

TADA2A

TADA2A

Rabbit

Transcriptional adapter 2-alpha

NM_001488

LEYKSALLNECNKQGGLRLAQARALIKIDVNKTRKIYDFLIREGYITKG