TAF5L Antilichaam - middengebied: HRP (ARP32565_P050-HRP)

TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF) -associated factor, 65kDa

PAF65B

27097

O75529

NP_055224

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human TAF5L

TAF5L functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

HECW2; UBC; KAT2B; LSM11; TADA3; TAF10; ELAVL1; TSC22D1; TTR; H2AFX; CDKN1A; ANXA7; KAT2A; TP53; ATXN7; CEBPE; USP22; ATXN7L3; SUPT3H; TAF9; MYC

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

66kDa

Ravnskjaer, K., (2007) EMBO J. 26 (12), 2880-2889

Wet Ice

589

TAF5L

TAF5L

Rabbit

TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

NM_014409

CVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNG

5L