Tafamidis
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A potent and selective transthyretin (TTR) kinetic stabilizer. It binds selectively and with negative cooperativity to the two normally unoccupied thyroxine binding sites of the TTR tetramer (Kd = ~2 and ~200 nM) 1. Stabilizes wild-type and mutant TTR under varying conditions in vitro (EC50=2.7-3.2 M) .1 Clinically useful for the treatment of familial amyloid polyneuropathy2,3 and TTR-related cardiomyopathy4.
Unconjugated
Off-white solid
-20°C
Beschrijving
Tafamidis Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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