TAK-243 (MLN7243)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1450833-55-2
C13356-2mg
E1 Activating
Ubiquitin
N[S; v6] (=O) (=O) OCC1CC (NC2=CC=NC3=CC (=N[N]23) C4=CC (=CC=C4) SC (F) (F) F) C (O) C1O
C19H20F3N5O5S2
TAK-243 (MLN7243) is a potent, mechanism-based small-molecule inhibitor of the ubiquitin activating enzyme (UAE) with an IC50 of 1 ± 0.2 nM in the UBCH10 E2 thioester assay. It has minimal inhibitory activity in a panel of kinase and receptor assays, as well as on human carbonic anhydrase type I and type II. TAK-243 (MLN7243) induces ER stress, abrogates NFκB pathway activation and promotes apoptosis.
3 years -20°C powder
Beschrijving
TAK-243 (MLN7243) Beschikbaar in 2 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
MS10
Each
MS pipette, variable vol µme 10~100 µL
MSP-100
1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
MSP-12X20
1 Unit
MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
1 Unit
MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NOR-30
1 Unit
MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRC-3001
1 Unit
MS pipette, variable vol µme 1000~10000 µL
MSP-10000
1 Unit