TAL-1 (fosfo Ser122) Antilichaam

TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

6886

P17542

NP_001274276.1

Human, Rat

TAL-1 (phospho Ser122) antibody was raised against a peptide sequence around phosphorylation site of Serine 122 (Q-L-S (p) -P-P) derived from Human TAL-1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

45 kDa

IgG

The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122.

Western Blot: 1:500~1:1000

TAL1

T-cell acute lymphocytic leukemia 1

Homo sapiens

Aplan P.D., Mol. Cell. Biol. 10:6426-6435 (1990) .

Gregory S.G., Nature 441:315-321 (2006) .

Chen Q., J. Exp. Med. 172:1403-1408 (1990) .

SCL, TAL1, TCL5

WB

4507363

Liquid