Talaporfine-13C4,15N

Talaporfin-13C4,15N (ME2906 (free acid) -13C4,15N) is the 13C- and 15N-labeled Talaporfin. Talaporfin sodium, can be used in intraoperative photodynamic therapy (PDT) with a 664-nm semiconductor laser, was evaluated for efficacy and safety in treating primary malignant parenchymal brain tumors[1].

ME2906 (free acid) -13C4,15N; Mono-L-aspartyl chlorin e6 (free acid) -13C4,15N; NPe6 (free acid) -13C4,15N

12352005

Isotope-Labeled Compounds; Photosensitizer

Apoptosis; Others

Cancer-programmed cell death

Cancer

CC1=C2/C=C(N=C3/C(CC([15N]([13C@@H]([13CH2][13C](O)=O)[13C](O)=O)[H])=O)=C(N/C4=C\C(C(CC)=C/5C)=NC5=C/C(N2)=C1C=C)/C(C(O)=O)=C4C)/[C@H]([C@@H]3CCC(O)=O)C

C34 13C4H41N4 15NO9

716.72

[1]Phase II clinical study on intraoperative photodynamic therapy with talaporfin sodium and semiconductor laser in patients with malignant brain tumors

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W769206/

Isotope-Labeled Compounds

No Development Reported