Tanzisertib HCl (CC-930)
Gecertificeerd

Tanzisertib HCl (CC-930)

Catalog #: C13446-01
Maat: 5 mg
Droogijs Vereist

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

CAS Number

2517855-91-1

Synonyms

JNK-930, JNKI-1

SKU

C13446-5mg

Target

JNK

Applications

MAPK

Smiles

C1CC (CCC1NC2=NC=C3C (=N2) N (C (=N3) NC4=C (C=C (C=C4F) F) F) C5CCOC5) O

Molecular Formula

C21H23F3N6O2.HCl

Additionnal Information

Tanzisertib HCl (CC-930, JNK-930, JNKI-1) is kinetically competitive with ATP in the JNK-dependent phosphorylation of the protein substrate c-Jun and potent against all isoforms of JNK (Ki (JNK1) = 44 ± 3 nM, IC50 (JNK1) = 61 nM, Ki (JNK2) = 6.2 ± 0.6 nM, IC50 (JNK2) = 5 nM, IC50 (JNK3) = 5 nM) and selective against MAP kinases ERK1 and p38a with IC50 of 0.48 and 3.4 μM respectively.

Storage Conditions

2 years -80 in solvent

Beschrijving

Tanzisertib HCl (CC-930) Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamTanzisertib HCl (CC-930)
Categorie
Beschikbare grootte5 mg
CatalogusnummerC13446-01