Taprizosine (mesilaat)

Taprizosin (UK-338003) mesylate is an α-adrenoreceptor antagonist[1].

358632-25-4

UK-338003 (mesylate)

12352005

Adrenergic Receptor

GPCR/G Protein; Neuronal Signaling

Neurological Disease; Cardiovascular Disease

CS(=O)(NC1=CC=CC2=C1CCN(C3=NC(N)=C4C(C5=NC=CC=C5)=C(OC)C(OC)=CC4=N3)C2)=O.CS(=O)(O)=O

C26H30N6O7S2

602.68

[1]Collett A, et al. Investigation of regional mechanisms responsible for poor oral absorption in humans of a modified release preparation of the alpha-adrenoreceptor antagonist, 4-amino-6,7-dimethoxy-2- (5-methanesulfonamido-1,2,3,4 tetrahydroisoquinol-2-yl) -5- (2-pyridyl) quinazoline (UK-338,003) : the rational use of ex vivo intestine to predict in vivo absorption. Drug Metab Dispos. 2008 Jan;36 (1) :87-94.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-19475A/

Reference compound1

No Development Reported