TARDBP Antilichaam

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

23435

Q13148

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TARDBP (NP_031401.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Neuroscience

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 42kDa

IgG

TARDBP

Jurkat

SW620

HT-29

A-673

Es-2

TAR DNA binding protein

Homo sapiens

TDP43 Antibody: ALS10, TDP-43, TDP43, TAR DNA-binding protein 43

WB, IHC, IF, IP, RIP

Liquid