TARDBP Antilichaam/TAR DNA-bindingseiwit 43 / TDP43

TDP-43 participates in stress-responsive ribonucleoprotein remodeling and interacts with components of transcription, splicing, and translation pathways. Changes in localization, solubility, or post-translational status are widely monitored as readouts in studies of RNA metabolism, proteostasis, and cellular stress adaptation across model systems. The TARDBP antibody enables specific detection of endogenous TDP-43 in applications such as western blot, immunofluorescence, immunohistochemistry, and immunoprecipitation. Researchers use the TARDBP antibody from NSJ Bioreagents to quantify total protein, assess nuclear"“cytoplasmic distribution, and evaluate biochemical fractionation outputs. With high specificity and consistent performance, the TARDBP antibody supports rigorous analysis of RNA-binding protein networks and RNA processing dynamics. TARDBP antibody

Western blot: 1:500-1:2000

Q13148

Human, Mouse, Rat

A peptide sequence specific to TAR DNA binding protein 43 was used as the immunogen for the TARDBP antibody.

ABAB-20

WB

Affinity chromatography

Purified

This TARDBP antibody is available for research use only.

After reconstitution, the TARDBP Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Optimal dilution of the TARDBP antibody should be determined by the researcher.

Nuclear, cytoplasmic

Western blot testing of 1) mouse brain, 2) mouse skin and 3) rat brain tissue lysate with TARDBP antibody. Predicted molecular weight ~45 kDa, commonly observed at 43-45 kDa.