Taurine-15N

Taurine-15N (2-Aminoethanesulfonic acid-15N) is 15N labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].

127041-63-8

2-Aminoethanesulfonic acid-15N

12352211

Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds

Autophagy; Metabolic Enzyme/Protease; Others

Metabolism-protein/nucleotide metabolism

Metabolic Disease; Cancer

O=S(CC[15NH2])(O)=O

C2H7 15NO3S

126.14

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Ripps H, Shen W. Review: taurine: a "very essential" amino acid. Mol Vis. 2012;18:2673-2686.|[3]Xu YJ, et al. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13 (2) :57-65.|[4]Kaneko H, et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 2018;50 (5) :527-535.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W727893/

Isotope-Labeled Compounds

No Development Reported