Taurochenodeoxycholzuur (standaard)

Taurochenodeoxycholic acid (Standard) is the analytical standard of Taurochenodeoxycholic acid. This product is intended for research and analytical applications. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties[1][2].

516-35-8

12-Deoxycholyltaurine (Standard)

12352211

H225, H301+H311+H331, H370

Apoptosis; Caspase; Endogenous Metabolite; Reference Standards

Apoptosis; Metabolic Enzyme/Protease; Others

COVID-19-immunoregulation

Inflammation/Immunology

99.67

C[C@@]1([C@@]2([H])[C@H](C)CCC(NCCS(=O)(O)=O)=O)[C@](CC2)([H])[C@@]([C@@H](C[C@]3([H])C[C@H](O)CC4)O)([H])[C@]([C@]34C)([H])CC1

C26H45NO6S

499.70

H225, H301+H311+H331, H370

[1]Wang X, et al. Taurochenodeoxycholic acid induces NR8383 cells apoptosis via PKC/JNK-dependent pathway. Eur J Pharmacol. 2016 Sep 5;786:109-15.|[2]Zhou C, et al. The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice. Pak J Pharm Sci. 2013 Jul;26 (4) :761-5.|[3]Uchida A, et al. Taurochenodeoxycholic acid ameliorates and ursodeoxycholic acid exacerbates small intestinal inflammation. Am J Physiol. 1997 May;272 (5 Pt 1) :G1249-57.|[4]Liu M, et al. Effects of taurochenodeoxycholic acid on adjuvant arthritis in rats. Int Immunopharmacol. 2011 Dec;11 (12) :2150-8.

Blue Ice

-20°C, sealed storage, away from light and moisture

http://file.medchemexpress.com/batch_PDF/HY-N2027R/Taurochenodeoxycholic-acid-Standard-SDS-MedChemExpress.pdf

Reference Standards