Taurolidine-d6

Taurolidine-d6 is the deuterium labeled Taurolidine. Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality[1][2].

12352005

Antibiotic; Apoptosis; Autophagy; Bacterial; Isotope-Labeled Compounds

Anti-infection; Apoptosis; Autophagy; Others

Cancer-programmed cell death

Cancer

O=S1(NC([2H])(N(CC1)C([2H])(N2C([2H])(NS(CC2)(=O)=O)[2H])[2H])[2H])=O

C7H10D6N4O4S2

290.39

[1]Marley K, et al. The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro. BMC Vet Res. 2013 Jan 18;9:15.|[2]Huang J, et al. Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance. Proc Natl Acad Sci U S A. 2022 May 10;119 (19) :e2121244119.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W744578/

Isotope-Labeled Compounds

No Development Reported