TBC1D10C Antilichaam - N-terminaal gebied: Biotine (ARP55893 P050-Biotine)

TBC1 domain family, member 10C

EPI64C, CARABIN

374403

Q8IV04

NP_940919

Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human TBC1D10C

TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]) .[supplied by OMIM].

NOTCH2NL; KRTAP13-1; KLHL12; KRTAP5-9; HOXA1; APP; PPP3R2

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Pig: 93%; Rat: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Pan, F., (2007) Nature 445 (7126), 433-436

Wet Ice

446

TBC1D10C

TBC1D10C

Rabbit

Carabin

NM_198517

MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEP