
TBK1/IKKε-IN-5
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1893397-65-3
Compound 1
C13785-100mg
IκB/IKK
NF-κB
C1COCCC1OC2=C (C=C (C=C2) C3=NC (=NC=N3) NC4=CC=C (C=C4) N5CCN (CC5) C6COC6) C#N
C28H31N7O3
TBK1/IKKε-IN-5 (compound 1) is a dual inhibitor of TANK-binding kinase 1 (TBK1) and IκB kinase-ε (IKKε/IKK-i) with IC50 of 1.0 nM and 5.6 nM for TBK1 and IKKε, respectively. TBK1/IKKε inhibition enhances response to PD-1 blockade, which effectively predicts tumor response in vivo.
3 years -20°C powder
Beschrijving
TBK1/IKKε-IN-5 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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