TBK1/IKKε-IN-5
Gecertificeerd

TBK1/IKKε-IN-5

Catalog #: C13785-01
Maat: 5 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

CAS Number

1893397-65-3

Synonyms

Compound 1

SKU

C13785-100mg

Target

IκB/IKK

Applications

NF-κB

Smiles

C1COCCC1OC2=C (C=C (C=C2) C3=NC (=NC=N3) NC4=CC=C (C=C4) N5CCN (CC5) C6COC6) C#N

Molecular Formula

C28H31N7O3

Additionnal Information

TBK1/IKKε-IN-5 (compound 1) is a dual inhibitor of TANK-binding kinase 1 (TBK1) and IκB kinase-ε (IKKε/IKK-i) with IC50 of 1.0 nM and 5.6 nM for TBK1 and IKKε, respectively. TBK1/IKKε inhibition enhances response to PD-1 blockade, which effectively predicts tumor response in vivo.

Storage Conditions

3 years -20°C powder

Beschrijving

TBK1/IKKε-IN-5 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamTBK1/IKKε-IN-5
Categorie
Beschikbare grootte5 mg
CatalogusnummerC13785-01