TBL1XR1 Antilichaam

This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta) -like 1X-linked (TBL1X) . The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.

79718

Q9BZK7

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human TBL1XR1 (NP_078941.2) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction

Affinity purification

Jurkat

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 55-70kDa

IgG

TBL1XR1

HepG2

NCI-H460

THP-1

Mouse brain

Mouse spleen

F-box-like/WD repeat-containing protein TBL1XR1

Homo sapiens

F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1, TBL1XR1, IRA1, TBLR1

WB, IF

Liquid