TCF7L2 Polyklonale Antilichaam, APC-Cy7 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
TCF4; TCF-4; Transcription factor 7-like 2; HMG box transcription factor 4; T-cell-specific transcription factor 4; T-cell factor 4; hTCF-4; TCF7L2
6934
Q9NQB0
Nucleus
• Rabbit
Rat
401-550/619
TCF7L2
• Polyclonal
• IgG
APC-Cy7
KLH conjugated synthetic peptide derived from human TCF7L2
IF (IHC-P), IF (IHC-F), IF (ICC)
Purified by Protein A.
650nm/780nm
1µg/µl
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
6934
Human, Mouse, Dog, Cow, Pig, Chicken
Beschrijving
TCF7L2 Polyklonale Antilichaam, APC-Cy7 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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