TCR Recombinant antilichaam [H57-597]

Annexin A1

Annexin A1; Annexin I; annexin I (lipocortin I) ; annexin-1; ANX1; calpactin II; calpactin-2; chromobindin-9; epididymis secretory sperm binding protein; Lipocortin I; LPC1; p35; phospholipase A2 inhibitory protein.

301

P17643

Human

Peptide "AAYLQETGKPLDETLK" derived from Annexin A1 conjugated to KLH.

Recombinant Monoclonal Antibody

Immunoaffinity enrichment of peptides coupled to targeted, multiple reaction monitoring mass spectrometry

Purified

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity (PubMed:8425544) . Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response (By similarity) . Promotes resolution of inflammation and wound healing (PubMed:25664854) . Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades (PubMed:15187149, PubMed:25664854) . Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (PubMed:15187149) . Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells (PubMed:17008549) . Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells (PubMed:17008549) . Has no effect on unstimulated T cells (PubMed:17008549) . Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration (PubMed:15187149) . Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton (PubMed:19625660) . Has high affinity for Ca (2+) and can bind up to eight Ca (2+) ions (By similarity) . Displays Ca (2+) -dependent binding to phospholipid membranes (PubMed:2532504, PubMed:8557678) . Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca (2+) -dependent interaction between phagosomes and the actin cytoskeleton (By similarity) .

ANXA1

Rabbit

Annexin A1

ANXA1