TCTEX1D3 Antilichaam

TCTEX1D3 Antibody: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A) . TCTEX1D3, also called TCTE3, has been identified as a gene responsible for congenital diaphragmatic hernia (CDH) .

6991

Q8IZS6

NP_777570

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

TCTEX1D3 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1287 - EL4 Cell Lysate

1 mg/mL

TCTEX1D3 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TCTEX1D3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

22 kDa

IgG

TCTEX1D3 is predicted to not cross-react with other members of the TCTEX-type family

TCTE3

Cat. No. 11-701 - Human Testis Tissue Slide

T-complex-associated-testis-expressed 3

Homo sapiens

He Y, Francis F, Myers KA, et al. Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments. J. Cell Biol. 2005; 168:697-703.

Li J, Lee WL, and Cooper JA. NudEL targets dynein to microtubule ends through LIS1. Nat. Cell Biol. 2005; 7:686-90.

Watanabe TK, Fujiwara T, Shimizu F, et al. Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1 to 6q. Cytogenet. Cell Genet. 1996; 73:153-6.

Chuang JZ, Yeh TY, Bollati F, et al. The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth. Dev. Cell 2005; 9:75-86.

TCTEX1D3 Antibody: TCTEX1D3, TCTEX1D3, Tctex1 domain-containing protein 3, T-complex testis-specific protein 3, Tcte-3

ELISA, WB, IF

28372535

Liquid