TCTEX1D4 Antilichaam

TCTEX1D4 Antibody: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A) . TCTEX1D4, also called TCTEX2 beta, interacts with different members of the TGF-beta receptor family, and when overexpressed, inhibits TGF-beta signaling.

343521

Q5JR98

NP_001013654

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

TCTEX1D4 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1404 - Mouse Liver Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Pig: (74%)

TCTEX1D4 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TCTEX1D4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

24 kDa

IgG

TCTEX1D4 is predicted to not cross-react with other members of the TCTEX-type family.

TCTEX1D4

Cat. No. 10-201 - Human Liver Tissue Slide

Tctex1 domain containing 4

Homo sapiens

He Y, Francis F, Myers KA, et al. Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments. J. Cell Biol. 2005; 168:697-703.

Li J, Lee WL, and Cooper JA. NudEL targets dynein to microtubule ends through LIS1. Nat. Cell Biol. 2005; 7:686-90.

Watanabe TK, Fujiwara T, Shimizu F, et al. Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1 to 6q. Cytogenet. Cell Genet. 1996; 73:153-6.

Chuang JZ, Yeh TY, Bollati F, et al. The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth. Dev. Cell 2005; 9:75-86.

TCTEX1D4 Antibody: Tctex1 domain-containing protein 4, Tctex-2-beta

ELISA, WB, IF

61966721

Liquid