TDO2 Antilichaam

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.

6999

P48775

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 21-260 of human TDO2 (NP_005642.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

HT-29

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 48kDa

IgG

WB: 1:500 - 1:2000

TDO2

Mouse liver

Mouse kidney

Mouse small intestine

Rat liver

Tryptophan 2,3-dioxygenase

Homo sapiens

TDO2, TDO, TPH2, TRPO, TO

WB

Liquid