TEAD2-eiwit, menselijk, recombinant (zijn & Myc)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
0.93
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') . May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
Ice Packs
-20°C
Beschrijving
TEAD2-eiwit, menselijk, recombinant (zijn & Myc) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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