Telisotuzumab (poeder)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Telisotuzumab (ABT-700) (powder) is a bivalent humanized IgG1 anti-c-Met monoclonal antibody. Telisotuzumab (powder) binds cellular c-Met and disrupts its productive dimerization and activation induced by HGF or by the high density of c-Met on the cell surface independent of ligand. Telisotuzumab (powder) induces apoptosis. Telisotuzumab (powder) can be used for the study of cancers harboring amplified MET, such as gastric and lung cancers[1].
1781223-80-0
ABT-700 (powder)
12352203
Apoptosis; c-Met/HGFR
Apoptosis; Protein Tyrosine Kinase/RTK
Cancer
[Telisotuzumab(powder)]
(146.1 kDa)
[1]Jieyi Wang, et al. Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification. BMC Cancer. 2016 Feb 16;16:105.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P99391A/
Inhibitory Antibodies
No Development Reported
Beschrijving
Telisotuzumab (ABT-700) (powder) is a bivalent humanized IgG1 anti-c-Met monoclonal antibody. Telisotuzumab (powder) binds cellular c-Met and disrupts its produ
Specificaties
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