TENM1 Antilichaam

The teneurin transmembrane protein 1 (TENM1) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2) . TENM1 is expressed primarily in the developing central nervous system and may be proteolytically cleaved with the intracellular domain translocating to the nucleus (3) . TENM1 is a direct target of the homeobox transcription factor EMX2, a transcription factor thought to be important for area specification in the developing cortex (4) .

10178

Q9UKZ4

NP_001156750

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell, Neuroscience

TENM1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1303 - Human Brain Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Chicken: (83%)

TENM1 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TENM1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

TENM1 antibody is human, mouse and rat reactive. TENM1 antibody is predicted to not cross-react with other members of the TENM family.

TENM1

Teneurin transmembrane protein 1

Homo sapiens

Minet AD, Rubin BP, Tucker RP, et al. Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain. J. Cell Sci. 1999; 112:2019-32.

Rubin BP, Tucker RP, Martin D, et al. Tenurins: a novel family of neuronal cell surface proteins in vertebrates, homologous to the Drosophila pair-rule gene Ten-m. Dev. Biol. 1999; 216:195-209.

Kenzelmann D, Chiquet-Ehrismann R, Leachman NT, et al. Teneurin-1 is expressed in interconnected regions of the developing brain and processed in vivo. BMC Dev. Biol. 2008; 8:30.

Beckmann J, Vitobello A, Ferralli J, et al. Human teneruin-1 is a direct target of the homeobox transcription factor EMX2 at a novel alternate promoter. BMC Dev. Biol. 2011; 11:35.

Teneurin transmembrane protein 1, teneurin-1, ODZ1, ODZ3, TEN-M1, TNM, TNM1

ELISA, WB, IHC-P, IF

253970444

Liquid