Teprenone impurity 5

Teprenone Impurity 5 (5Z-GGA) is the cis-isomer of Teprenone. Teprenone Impurity 5 has inhibitory activity on the proliferation of human ovarian cancer cells Caov-3, and can block the invasion process of cancer cells. Teprenone Impurity 5 can induce the expression of heat shock protein 70 (HSP70) and thioredoxin (Trx). Teprenone Impurity 5 can be used for the research of ovarian cancer[1].

3796-67-6

12352211

H302-H315-H319-H335

Drug Isomer; HSP; TrxR

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Cancer

C/C(C)=C\CC/C(C)=C\CC/C(C)=C\CC/C(C)=C\CCC(C)=O

C23H38O

330.55

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

[1]Xizhen Zhu, et al. Application of teprenone and derivatives thereof in preparation of medicines for preventing and treating ovarian cancer. CN110882237A. 2020-03-17

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-Z15805/

Reference compound1

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