TERF2 Antilichaam - C-terminaal gebied: Biotine (ARP30228_T100-Biotine)

Telomeric repeat binding factor 2

TRF2, TRBF2

7014

Q15554

NP_005643

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human TERF2

TERF2 is a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; TERF2IP; TINF2; EP300; SLX4; RPA3; RPA2; RPA1; BMI1; DCLRE1B; BLM; ATM; VCP; NBN; MRE11A; HMGA1; RAD50; TOP3A; HSP90AA1; TEP1; SF3B2; TOP2A; TFAP4; OCM2; NUMA1; NCL; NASP; HMGN2; HMGN1; HMGB1; H2AFX; XRCC6; CTBP1; ASS1; APEX1; ANXA5; DDX39A; HMGN3; D

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

55kDa

Etheridge, K.T., (2008) J. Biol. Chem. 283 (11), 6935-6941

Wet Ice

500

TERF2

TERF2

Rabbit

Telomeric repeat-binding factor 2

NM_005652

TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN