Tersolisib (STX-478)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2883540-92-7
C01887-5mg
PI3K
PI3K/Akt/mTOR
Tersolisib (STX-478) is a highly potent, mutant-selective, allosteric inhibitor of PI3Kα, that selectively targets prevalent mutant forms of PI3Kα. It demonstrates strong efficacy against common PI3Kα helical- and kinase-domain mutations, including the H1047R variant, with an IC50 value of 9.4 nmol/L. STX-478 exhibits 14-fold greater selectivity for mutant PI3Kα over the wild-type form. It spares metabolic dysfunction and improves therapeutic response in PI3Kα-Mutant Xenografts.
Beschrijving
Tersolisib (STX-478) Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
NP (4-hydroxy-3-nitrophenylacetate)
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NP (4-hydroxy-3-nitrophenylacetate)
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ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Disc Membrane Hydrophobic PTFE, 0.22μm
CPTB14222
50 PCS
Rat Serum Albumin
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Denhardt's Solution (50X)
EC-915
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FKBP4, ID (FK506-binding Protein 4, Peptidyl-prolyl cis-trans Isomerase FKBP4, PPIase FKBP4, Rotamase, HSP-binding Immunophilin, HBI, FKBP52 Protein, 52kD FK506-binding Protein, 52kD FKBP, FKBP-52, 59kD Immunophilin, FKBP59, p59 Protein, FKBP-4, FKBP52)
MBS623609-01
0.2 mL
West Nile Virus, NS3 Protease (WNV)
MBS603723-01
0.1 mg
Recent gezochte producten
BSA and BGG Stock standards (1 vial each @ 2 mg/ml) for BCA Optima Protein Assay kit
BSA-BGG-1
1 PK
General Bovine Serum Albumin (BSA) ELISA Kit
DL-BSA-Ge-01
48 Tests
General Bovine Serum Albumin (BSA) ELISA Kit
RD-BSA-Ge-01
96 Tests
Heparin
BSA-Hep-01 – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03High – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03High – 50 mg
50 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03Low – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03Low – 50 mg
50 mg