TESPA1 Polyklonale Antilichaam, APC-vervoeging

Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity) . Plays a role in T-cell antigen receptor (TCR) -mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release and mitochondrial Ca2+ uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.

Protein TESPA1; TESPA1; Thymocyte-expressed positive selection-associated protein 1; KIAA0748; HSPC257

9840

A2RU30

Cytoplasm

Human

231-330/521

TESPA1

APC

KLH conjugated synthetic peptide derived from human TESPA1

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

650nm/660nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

9840

Rabbit