Tetrabenazine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
718635-93-9
Ro 1-9569
C03699-5mg
VMAT
Transmembrane Transporters
Tetrabenazine (Ro 1-9569) is a non-competitive inhibitor of the vesicular monoamine transporter (VMAT), with a higher selectivity for VMAT2 over VMAT1. It exhibits an IC50 of 0.3 μM for VMAT2 and 3 μM for VMAT1, and a Kd of 60 nM for VMAT2 and 9.38 nM for VMAT1. It treats Huntington’s chorea by reducing excessive dopaminergic activity and impairing monoamine storage in synaptic vesicles.
Beschrijving
Tetrabenazine Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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