Tetradecaandizuur-d24

Tetradecanedioic acid-d24 is the deuterium labeled Tetradecanedioic acid[1]. Tetradecanedioic acid is an endogenous metabolite and belongs to the class of organic compounds known as long-chain fatty acids. Tetradecanedioic acid can act as a candidate biomarker for organic anion-transporting polypeptide mediated agent-agent interactions[2].

130348-88-8

12352211

H302, H315, H319, H335

Endogenous Metabolite

Metabolic Enzyme/Protease

Metabolism-protein/nucleotide metabolism

Metabolic Disease

98.80

10 mM in DMSO

OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(O)=O)=O

C14H2D24O4

282.50

H302, H315, H319, H335

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Santockyte R, et al. LC-MS/MS bioanalysis of plasma 1, 14-tetradecanedioic acid and 1, 16-hexadecanedioic acid as candidate biomarkers for organic anion-transporting polypeptide mediated drug-drug interactions. Bioanalysis. 2018 Sep 1;10 (18) :1473-1485.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-W011819S/Tetradecanedioic-acid-d24-SDS-MedChemExpress.pdf

Isotope-Labeled Compounds

No Development Reported