Tetraethyleenglycolmonotosilaat
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
77544-60-6
Tos-PEG4
12352203
H301, H314
ADC Linker; PROTAC Linkers
Antibody-drug Conjugate/ADC Related; PROTAC
Cancer-programmed cell death
Cancer
97.92
10 mM in DMSO
OCCOCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O
C15H24O7S
348.42
H301, H314
[1]Park KD, et al. Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers.Chem Biol. 2009 Jul 31;16 (7) :763-72.
Room Temperature
-20°C, 3 years; 4°C, 2 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-41541/Tetraethylene-glycol-monotosylate-SDS-MedChemExpress.pdf
ADC Related
No Development Reported
Cleavable Linker; PEG Linkers
Beschrijving
Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Tetraethylene
Specificaties
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