Tetrahydroberine

Tetrahydroberberine is a different kind of living thing that can be extended and divided into parts. Tetrahydroberberine is a kind of effective D2 receptor antagonistic force. Tetrahydroberberine has the ability to strengthen the stomach and relieve the pressure on the stomach[1][2][3].

522-97-4

Canadine

12352005

H302

Dopamine Receptor

GPCR/G Protein; Neuronal Signaling

Neuroscience-Neuromodulation

Neurological Disease

98.61

DMSO : 25 mg/mL (ultrasonic)

COC1=CC=C(CC23)C(CN2CCC(C3=C4)=CC5=C4OCO5)=C1OC

C20H21NO4

339.39

H302

[1]Lee TH, et al. Tetrahydroberberine, an isoquinoline alkaloid isolated from corydalis tuber, enhances gastrointestinal motor function. J Pharmacol Exp Ther. 2011 Sep;338 (3) :917-24.|[2]Niwa M, et al. Dopaminergic unique affinity of tetrahydroberberine and l-tetrahydroberberine-d-camphor sulfonate. Pharmacology. 1991;43 (6) :329-36.|[3]Wu C, et al. Tetrahydroberberine blocks ATP-sensitive potassium channels in dopamine neurons acutely-dissociated from rat substantia nigra pars compacta. Neuropharmacology. 2010 Dec;59 (7-8) :567-72.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-N0925/Tetrahydroberberine-SDS-MedChemExpress.pdf

Natural Products

No Development Reported

5-HT1 Receptor