Tetramethylrhodamine-5-isothiocyanaat

Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL) . Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly (lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles[1][2].

80724-19-2

12171500

H315-H317-H319-H330-H334-H335-H351-H412

Fluorescent Dye

Others

Cancer

10 mM in DMSO

CN(C1=CC2=[O+]C3=C(C=CC(N(C)C)=C3)C(C4=CC=C(N=C=S)C=C4C([O-])=O)=C2C=C1)C

C25H21N3O3S

443.52

P260-P261-P264-P271-P272-P273-P280-P284-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

[1]Alayed KM, et al. Immunostaining for rapid diagnosis of acute promyelocytic leukemia with the tetramethylrhodamine-5-isothiocyanate-conjugated anti-promyelocytic leukemia monoclonal antibody PG-M3. Arch Pathol Lab Med. 2013 Nov;137 (11) :1669-73.|[2]Navarro SM, et al. Biodistribution of PLGA and PLGA/chitosan nanoparticles after repeat-dose oral delivery in F344 rats for 7 days. Ther Deliv. 2014 Nov;5 (11) :1191-201.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-D0153/

Dye Reagents

No Development Reported