Tetraxetan (standaard)

Tetraxetan (Standard) is the analytical standard of Tetraxetan. This product is intended for research and analytical applications. Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer)[2][3].

60239-18-1

DOTA (Standard)

12352005

Biochemical Assay Reagents; Radionuclide-Drug Conjugates (RDCs) ; Reference Standards

Antibody-drug Conjugate/ADC Related; Others

Cancer

O=C(O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1

C16H28N4O8

404.42

[1]Orcutt KD, et al. Biodistribution and clearance of small molecule hapten chelates for pretargeted radioimmunotherapy. Mol Imaging Biol. 2011 Apr;13 (2) :215-21.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W053583R/

Reference Standards