Tetrazine-amine (monohydrochloride)

Tetrazine-Amine monohydrochloride is the monohydrochloride form of Tetrazine-Amine. Tetrazine-amine is a Tetrazine linker that can be used to covalently label living cells by cycloaddition[1][2]. Tetrazine-Amine (monohydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

1416711-59-5

(4- (1,2,4,5-Tetrazin-3-yl) phenyl) methanamine (monohydrochloride) ; Tetrazine-NH2 (monohydrochloride)

12352005

H302, H315, H319, H335

Biochemical Assay Reagents

Others

Cancer-programmed cell death

Cancer

99.93

DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 70°C) |H2O : ≥ 100 mg/mL

NCC1=CC=C(C2=NN=CN=N2)C=C1.Cl

C9H10ClN5

223.67

H302, H315, H319, H335

[1]Devaraj NK, et, al. Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl. 2009;48 (38) :7013-6. |[2]Devaraj NK, et, al. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem. 2008 Dec;19 (12) :2297-9.

Room Temperature

4°C (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-W053709A/Tetrazine-Amine-monohydrochloride-SDS-MedChemExpress.pdf

Reference compound1

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