TFAM Antilichaam - middengebied: Biotine (ARP36992_P050-Biotine)

Transcription factor A, mitochondrial

Hmgt, mtTF, tsHM, Hmgts, mtTFA, tsHMG, AI661103

21780

P40630

NP_033386

Mouse, Rat, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of mouse TFAM

TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.

C1QBP; SNCA

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Mouse: 100%; Rabbit: 77%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

27kDa

Noack, H., et al., (2006) Biochim. Biophys. Acta 1760 (2), 141-150

Wet Ice

243

TFAM

TFAM

Rabbit

Transcription factor A, mitochondrial

NM_009360

SESFQEAKDDSAQGKLKLVNEAWKNLSPEEKQAYIQLAKDDRIRYDNEMK