TFB2M Antilichaam - N-terminalgebied: HRP (ARP34471_T100-HRP)

Transcription factor B2, mitochondrial

Hkp1, mtTFB2

64216

Q9H5Q4

NP_071761

Human, Rat, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human TFB2M

TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

UBC; FBXO6; C1QBP; CUL3; TFB2M; POLRMT; TFAM; PNP

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Horse: 100%; Human: 100%; Rabbit: 83%; Rat: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

45kDa

Falkenberg, M., (2002) Nat. Genet. 31 (3), 289-294

Wet Ice

396

TFB2M

TFB2M

Rabbit

Dimethyladenosine transferase 2, mitochondrial

NM_022366

ECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCD