TFF-2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma (Nikolaidis, N.M. et al. Am. Journal Respir. Cell Mol. Biol. (2003) 4: 458-464) . Recombinant human TFF2 is a 12.0 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
TFF2; SP; SML1
7032
Q03403
NP_005414.1
NM_005423
21q22.3
Human
Human, Mouse
AEKPSPCQCS RLSPHNRTNC GFPGITSDQC FDNGCCFDSS VTGVPWCFHP LPKQESDQCV MEVSDRRNCG YPGISPEECA SRKCCFSNFI FEVPWCFFPK SVEDCHY
< 0.1 ng/µg of protein (< 1EU/µg)
> 98% by SDS-PAGE & HPLC analyses
Assay #1: Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 µg/ml. Assay #2: Determined by its ability to chemoattract human MCF-7 cells using a concentration range of 1.0-10.0 ng/ml.
107
Lyophilized
12 kDa
E. coli
Beschrijving
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defens
Specificaties
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