TFPI-antilichaam

TFPI Antibody: Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF) -dependent pathway of blood coagulation (1) . TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop (1) .

7035

P10646

NP_006278

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

TFPI Antibody is affinity chromatography purified via peptide column.

Cat. No. 1468 - Rat Small Intestine Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Rabbit: (92%)

TFPI Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TFPI antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

TFPI antibody is human, mouse and rat reactive. At least two isoforms of TFPI are known to exist; this antibody will detect both isoforms.

TFPI

Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

Homo sapiens

Broze GJ Jr and Girard TJ. Tissue factor pathway inhibitor: structure-function. Front. Biosci. 17:262-80.

TFPI Antibody: EPI, TFI, LACI, TFPI1, Tissue factor pathway inhibitor, Extrinsic pathway inhibitor, TFPI

ELISA, WB, IHC-P, IF

5454114

Liquid