TG Antilichaam

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

7038

P01266

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 2469-2768 of human TG (NP_003226.4) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Growth Factors, Signal Transduction

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 290kDa

IgG

WB: 1:500 - 1:2000

TG

Thyroglobulin

Homo sapiens

TG, AITD3, TDH3, Thyroglobulin, TGN

WB

Liquid